反应详情

2-Formylquinoxaline-1,4-dioxide hydrate 4 g (0.02 mole) was dissolved at 60°-65° C. in 30 ml methanol containing 2-4 drops of triethylamine. The solution was agitated and 1.5 g (0.0246 mole) of ethanolamine was added. The heat source was removed and the mixture was then allowed to cool slowly to room temperature with stirring. There was obtained a precipitate of 2-(2-oxazolidinyl)quinoxaline-1,4-dioxide (hereinafter designated P-2244 for convenience). The precipitate was filtered, rinsed with a small amount of methanol, then dried. The resulting product had a melting point of 153°-154° C. and analyzed as follows:

1. customThe heat source was removed
2. stirringwith stirring