Ethanolamine → HCID 178526234, compound

HRID 1733218Notes

Reaction equation

HRID 1733218 reaction equation
O.[CH:2]([C:4]1[CH:13]=[N+:12]([O-:14])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:15])=[O:3].[CH2:16]([CH2:18][NH2:19])O>CO.C(N(CC)CC)C>[O:3]1[CH2:16][CH2:18][NH:19][CH:2]1[C:4]1[CH:13]=[N+:12]([O-:14])[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N+:5]=1[O-:15]

Participants

5

Reactant 2

HCID 700EthanolamineHCID 1785269452-Formylquinoxaline-1,4-dioxide hydrate

Product 1

HCID 178526234HCID 178526234, compound

Reagents, catalysts & solvents 2

HCID 887MethanolCatalystHCID 8471TriethylamineSolvent

Procedure

2-Formylquinoxaline-1,4-dioxide hydrate 4 g (0.02 mole) was dissolved at 60°-65° C. in 30 ml methanol containing 2-4 drops of triethylamine. The solution was agitated and 1.5 g (0.0246 mole) of ethanolamine was added. The heat source was removed and the mixture was then allowed to cool slowly to room temperature with stirring. There was obtained a precipitate of 2-(2-oxazolidinyl)quinoxaline-1,4-dioxide (hereinafter designated P-2244 for convenience). The precipitate was filtered, rinsed with a small amount of methanol, then dried. The resulting product had a melting point of 153°-154° C. and analyzed as follows:

Workup

  1. customThe heat source was removed
  2. stirringwith stirring

Sources & evidence

ORD record
ord-9072884705c1461aa46b69ae7e870348
Source dataset
uspto-grants-1980_12
Patent number
US04241061

Reaction notes

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