Benzylamine → HCID 54084844, compound

HRID 1733233Notes

Reaction equation

HRID 1733233 reaction equation
O=[CH:2][C@@H:3]([C@H:5]([C@H:7]([C@@H:9]([CH2:11][OH:12])[OH:10])[OH:8])[OH:6])[OH:4].[CH2:13]([NH2:20])[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1.[Cl:21][CH2:22][CH2:23][N:24]=[C:25]=[O:26]>>[Cl:21][CH2:22][CH2:23][NH:24][C:25]([N:20]([CH2:13][C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1)[CH:2]1[O:10][C@H:9]([CH2:11][OH:12])[C@H:7]([OH:8])[C@H:5]([OH:6])[C@H:3]1[OH:4])=[O:26]

Participants

4

Reactant 3

HCID 7504BenzylamineHCID 160352-Chloroethyl isocyanateHCID 3037556(2R,3S,4S,5R)-2,3,4,5,6-pentahydroxyhexanal

Product 1

HCID 54084844HCID 54084844, compoundYield 65.4%

Procedure

3.6 g of D-galactose, 3.2 g of benzylamine and 3.0 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 23-(1). 4.9 g of 1-(2-chloroethyl)-3-benzyl-3-(D-galactopyranosyl)urea are thereby obtained as colorless caramel.

Sources & evidence

ORD record
ord-f2b84fff4dc84246a99b2ba5e0d2140d
Source dataset
uspto-grants-1980_12
Patent number
US04241052

Reaction notes

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