Furfurylamine → HCID 54542522, compound

HRID 1733253Notes

Reaction equation

HRID 1733253 reaction equation
O=[CH:2][C@@H:3]([C@@H:5]([C@@H:7]([CH2:9][OH:10])[OH:8])[OH:6])[OH:4].[CH2:11]([NH2:17])[C:12]1[O:16][CH:15]=[CH:14][CH:13]=1.[Cl:18][CH2:19][CH2:20][N:21]=[C:22]=[O:23]>>[Cl:18][CH2:19][CH2:20][NH:21][C:22]([N:17]([CH2:11][C:12]1[O:16][CH:15]=[CH:14][CH:13]=1)[CH:2]1[O:8][C@H:7]([CH2:9][OH:10])[C@@H:5]([OH:6])[C@H:3]1[OH:4])=[O:23]

Participants

4

Reactant 3

HCID 3438FurfurylamineHCID 160352-Chloroethyl isocyanateHCID 5311110Aldehydo-D-ribose

Product 1

HCID 54542522HCID 54542522, compoundYield 64.3%

Procedure

3.0 g of D-ribose, 2.8 g of furfurylamine and 2.5 g of 2-chloroethyl isocyanate are treated in the same manner as described in Example 31-(1). 4.3 g of 1-(2-chloroethyl)-3-furfuryl-3-(D-ribofuranosyl)urea are thereby obtained as colorless caramel.

Sources & evidence

ORD record
ord-e9e6ab90da174888ba7c36acc3b5438e
Source dataset
uspto-grants-1980_12
Patent number
US04241052

Reaction notes

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