反应详情

6.54 kg of 3-(p-tert.butyl-phenyl)-2-methyl-propionaldehyde and 3 kg of piperidine are heated at reflux overnight in 4.54 liters of toluene in a water-separator under nitrogen gasification and the toluene is distilled in vacuo. The residue is distilled in vacuo. There is obtained pure 1-[3-(p-tert.butyl-phenyl)-2-methyl-1-propenyl]-piperidine of boiling point 118°-120° C./0.026 Torr.

1. distillationthe toluene is distilled in vacuo
2. distillationThe residue is distilled in vacuo