Methyl iodide → HCID 178502511, compound

Participants

Reaction Steps

To a solution of 3-imino(2,6-dichloro)phenylmethyl-4-(3-carbomethoxythioureido)benzophenone (2.43 g.; 0.005 mole) in dimethylformamide (100 ml.) is added water (5.0 ml.) and then sodium hydroxide (50% aqueous; 0.4 g.; 0.005 mole). The solution is stirred for 11/2 hours and then methyl iodide (0.71 g.; 0.005 mole) is added. The solution is stirred for one-half hour. The precipitate which forms is collected by filtration and dried to afford 1.3 g. of 3-iminophenylmethyl-4-(3-carbomethoxy-S-methylisothioureido)benzophenone, m.p. 63°-68° C. (dec.).

Provenance & Evidence