Methyl iodide → HCID 178460710, compound

HRID 1733369Notes

Reaction equation

HRID 1733369 reaction equation
[NH:1]=[C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH3:11])=[C:4]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]1[NH:19][C:20]([NH:22][C:23]([O:25][CH3:26])=[O:24])=[S:21].[OH-].[Ca+2].[OH-].[CH3:30]I>CC(C)=O.O>[NH:1]=[C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH3:11])=[C:4]([CH2:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:3]1[NH:19][C:20](=[N:22][C:23]([O:25][CH3:26])=[O:24])[S:21][CH3:30]

Participants

6

Reactant 3

HCID 6328Methyl iodideHCID 6093208Calcium HydroxideHCID 131711976HCID 131711976, compound

Product 1

HCID 178460710HCID 178460710, compound

Reagents, catalysts & solvents 2

HCID 180AcetoneSolventHCID 962WaterSolvent

Procedure

To a solution of 1-iminophenylmethyl-2-(3-carbomethoxythioureido)-4-propylthiobenzene (3.88 g.; 0.01 mol) in acetone (40 ml.) and water (10 ml.) there is added calcium hydroxide (0.74 g.; 0.01 mol). The mixture is stirred at room temperature for 4 hours and then is added methyl iodide (1.42 g.; 0.01 mol). The mixture is stirred at room temperature for 4 hours and the precipitate collected and dried to afford 1-iminophenylmethyl-2-(3-carbomethoxy-S-methylisothioureido)-4-propylthiobenzene.

Workup

  1. stirringThe mixture is stirred at room temperature for 4 hours
  2. customthe precipitate collected
  3. customdried

Sources & evidence

ORD record
ord-c84c0f237f1443acafc6e15ec8db9878
Source dataset
uspto-grants-1980_12
Patent number
US04241079

Reaction notes

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