m-Chloroperbenzoic acid → HCID 178460999, compound

HRID 1733378Notes

Reaction equation

[NH:1]=[C:2]1[CH:7]=[CH:6][C:5]([S:8][CH2:9][CH2:10][CH3:11])=[C:4]([CH2:12][C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:3]1[NH:19][C:20](=[N:23][C:24]([O:26][CH3:27])=[O:25])[S:21][CH3:22].ClC1C=C(C=CC=1)C(OO)=[O:33]>C(Cl)Cl>[NH:1]=[C:2]1[CH:7]=[CH:6][C:5]([S:8]([CH2:9][CH2:10][CH3:11])=[O:33])=[C:4]([CH2:12][C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH:3]1[NH:19][C:20](=[N:23][C:24]([O:26][CH3:27])=[O:25])[S:21][CH3:22]

Participants

Conditions

Temperature: -5 °C

Procedure

To a solution of 1-iminophenylmethyl-2-(3-carbomethoxy-S-methylisothioureido)-4-n-propylthiobenzene (4.02 g.; 0.01 mol) in methylene chloride (50 ml.), cooled to -5° C., is added 85% of m-chloroperoxybenzoic acid (2.02 g.; 0.01 mol). The mixture is stirred at -5° C. for 30 minutes and is washed with aqueous sodium bicarbonate solution. The methylene dichloride is evaporated from the organic solution to afford 1-iminophenylmethyl-2-(3-carbomethoxy-S-methylisothioureido)-4-n-propylsulfinylbenzene.

Workup

washis washed with aqueous sodium bicarbonate solution
customThe methylene dichloride is evaporated from the organic solution

Sources & evidence

ORD record: ord-999ea2fe138340738149770e65be814c
Source dataset: uspto-grants-1980_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04241079

Reaction notes

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