Potassium Carbonate → HCID 20299770, compound

Participants

Reaction Steps

48 g of potassium carbonate were added to a solution of 17.8 g of the product of Step B in 180 ml of acetone and after the addition of 17.5 ml of 1-iodopropane, the mixture was refluxed under an inert atmosphere for 41/2 hours and was filtered. The filtrate was evaporated to dryness and the residue was taken up in ether. 100 ml of 2 N sodium hydroxide solution was added to the mixture and the decanted organic phase was washed with water, dried and evaporated to dryness to obtain 19.25 g of N-(2-cyclohexylethyl)-3-methoxy-N-propyl-benzeneethanamine in the form of a yellow oil which was used as is for the next step.

Provenance & Evidence