HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetohydrazide → 3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-a]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetohydrazide | HCID 14039 | — |
| Reactant | HCID 15192309 | HCID 15192309 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | 3-Methyl-6-[3-(trifluoromethyl)phenyl]-1,2,4-triazolo[4,3-a]pyridine | HCID 20296334 | — |
Reaction Steps
A mixture of 2 g. of 2-chloro-5-[3-(trifluoromethyl)phenyl]pyridine and two equivalents of acetylhydrazine in n-butanol is heated at reflux for 48 hours to give the product of the Example as crystals, m.p. 185°-187° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04242515 |
| Source dataset | uspto-grants-1980_12 |
| ORD ID | ord-a119ef3f73d248b681e2f96e273e06de |
| Source note | uspto-grants-1980_12 |