HCID 43218479, compound → HCID 20300160, compound

Participants

Reaction Conditions

Reaction Steps

23.8 parts of 3-(benzoylmethylthio)-propionic acid methyl ester are added in the course of 30 minutes to 36 parts of a 30 percent strength by weight NaOCH3 /MeOH solution which has been cooled to 0° C., and the mixture is stirred for 2 hours at from 0° to 10° C. The end product is isolated from the reaction mixture by the method described in Example 14(b). 18.5 parts (90% of theory) of 3-hydroxy-2-benzoyldihydrothiophene of boiling point 137°-140° C./0.16-0.08 mbar are obtained.

Provenance & Evidence