Triethylamine → HCID 20300004, compound

HRID 1733693Notes

Reaction equation

HRID 1733693 reaction equation
[OH:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[N:3]1.C(N(CC)CC)C.[CH2:18]([S:22](Cl)(=[O:24])=[O:23])[CH2:19][CH2:20][CH3:21]>C1C=CC=CC=1>[CH2:18]([S:22]([O:1][N:2]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[N:4]=[N:3]1)(=[O:24])=[O:23])[CH2:19][CH2:20][CH3:21]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 754301-Butanesulfonyl chlorideHCID 757711-Hydroxybenzotriazole

Product 1

HCID 20300004HCID 20300004, compoundYield 96.7%

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent2×

Procedure

In benzene (50 ml) are dissolved 1-hydroxy-1,2,3-benzotriazole (6.8 g) and triethylamine (7.0 ml) and thereto is added dropwise a solution of n-butanesulfonyl chloride (7.8 g) in benzene (10 ml) at room temperature and the mixture is stirred for 4 hours. After the reaction, the benzene layer is separated, washed with water, dried over anhydrous magnesium sulfate and then concentrated to give 1-(n-butanesulfonyloxy)-1,2,3-benzotriazole (12.3 g) as an oily substance. Infrared spectrum (film): 1395, 1175 cm-1.

Workup

  1. customAfter the reaction
  2. customthe benzene layer is separated
  3. washwashed with water
  4. dry with materialdried over anhydrous magnesium sulfate
  5. concentrationconcentrated

Sources & evidence

ORD record
ord-9ea8dfa7099f4e0488d52603669c8e31
Source dataset
uspto-grants-1980_12
Patent number
US04242507

Reaction notes

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