huagongshe.com
HRID1733747

反应详情

EQUATION

反应方程式

HRID 1733747 的结构方程式

REACTANTS

反应物

4
结构：CC(=O)O
HCID176

Acetic Acid

C2H4O2

结构：CO
HCID887

Methanol

CH4O

结构：C1CCOC1
HCID8028

Tetrahydrofuran

C4H8O

结构：CCCON=C(C(=O)NC1C(=O)N2C(C(=O)OCc3ccc([N+](=O)[O-])cc3)=CCS[C@H]12)C1=CSCCO1
HCID131712015

未命名化合物

PRODUCTS

生成物

1
结构：CCCON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCS[C@H]12)C1=CSCCO1
HCID131712016

未命名化合物

收率 51.3%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：[C].[Pd]
催化剂HCID178418390

未命名化合物

结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

4-Nitrobenzyl 7-[2-(2,3-dihydro-1,4-oxathiin-6-yl)-2-n-propoxyiminoacetamido]-3-cephem-4-carboxylate (syn isomer, 6.7 g.), tetrahydrofuran (200 ml.), methanol (67 ml.), acetic acid (2 ml.), water (6 ml.) and 10% palladium-carbon (3.3 g.) were treated in a similar manner to that of Example 18-(2) to give 7-[2-(2,3-dihydro-1,4-oxathiin-6-yl)-2-n-propoxyiminoacetamido]-3-cephem-4-carboxylic acid (syn isomer, 2.59 g.).