反应详情

A solution of 4-(1H-imidazol-1-yl)-nitrobenzene (20 g; ~0.11 mol) in a mixture of 500 ml ethyl acetate and 500 ml ethanol was hydrogenated in a Parr hydrogenation apparatus at 28.12 kPa (40 psi) and 25° C. by using 0.5 g 5% Pd-C as a catalyst. The reaction mixture was filtered and evaporated in vacuo to give the title compound (14 g) as crystals. M.p. 142°-144° C.

1. customwas hydrogenated in a Parr hydrogenation apparatus at 28.12 kPa (40 psi) and 25° C.
2. filtrationThe reaction mixture was filtered
3. customevaporated in vacuo