Nitric Acid → HCID 19438795, compound

HRID 1733871Notes

Reaction equation

[C:1]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)=[CH:11][CH:10]=1)([C:3]([O:5][CH2:6][CH3:7])=[O:4])=[O:2].[N+:20]([O-])([OH:22])=[O:21]>>[C:1]([NH:8][C:9]1[CH:14]=[CH:13][C:12]([N:15]2[CH:19]=[CH:18][N:17]=[CH:16]2)=[CH:11][C:10]=1[N+:20]([O-:22])=[O:21])([C:3]([O:5][CH2:6][CH3:7])=[O:4])=[O:2]

Participants

Reactant 2

HCID 944Nitric Acid2×

HCID 19438777HCID 19438777, compound

Product 1

HCID 19438795HCID 19438795, compoundYield 80%

Procedure

1-Ethoxalylamino-4-(1H-imidazol-1-yl)-benzene (16 g; 61.8 mmol) was added gradually to 100 ml nitric acid (d=1.52) at 0° C. Stirring was continued at 0° C. for 1 h, and then the reaction mixture was poured into ice-water to give the title compound (18 g; 80%) as a nitric acid salt. M.p. 180° C. (decomp.).

Sources & evidence

ORD record: ord-f3a101583c774c09bec35f482b27b84a
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05532236

Reaction notes

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