Imidazole → HCID 19438797, compound

HRID 1733883Notes

Reaction equation

HRID 1733883 reaction equation
F[C:2]1[CH:11]=[C:10]2[C:5]([NH:6][C:7](=[O:16])[C:8]3[N:9]2[C:12](=[O:15])[NH:13][N:14]=3)=[CH:4][C:3]=1[N+:17]([O-:19])=[O:18].[NH:20]1[CH:24]=[CH:23][N:22]=[CH:21]1>CN(C)C=O>[N:20]1([C:2]2[CH:11]=[C:10]3[C:5]([NH:6][C:7](=[O:16])[C:8]4[N:9]3[C:12](=[O:15])[NH:13][N:14]=4)=[CH:4][C:3]=2[N+:17]([O-:19])=[O:18])[CH:24]=[CH:23][N:22]=[CH:21]1

Participants

4

Reactant 2

HCID 795ImidazoleHCID 19438785HCID 19438785, compound

Product 1

HCID 19438797HCID 19438797, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Conditions

Temperature
120 °C

Procedure

To a solution of 0.5 g (~1.89 mmol) 8-fluoro-7-nitro[1,2,4]triazolo[4.3-a]quinoxaline-1,4(2H,5H)-dione in 10 ml dry N,N-dimethylformamide was added 0.4 g (~5.9 mmol) imidazole. The reaction mixture was stirred at 120° C. for 2h. Evaporation in vacuo gave the title compound as an oil, which was solidified by stirring with water. Yield: 0.34 g (58%). M.p.>300° C. decomp.

Workup

  1. customEvaporation in vacuo

Sources & evidence

ORD record
ord-43fa1d3ed6994773adf6e105b2eb74f6
Source dataset
uspto-grants-1996_07
Patent number
US05532236

Reaction notes

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