HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 9834448, compound → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 9834448 | HCID 9834448 | — |
| Reactant | 5-{4-[4-(5-Cyano-1H-indol-3-yl)butyl]piperazin-1-yl}-1-benzofuran-2-carboxylic acid | HCID 11201569 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | Vilazodone | HCID 6918314 | — |
Reaction Steps
Analogously to Example 3, starting from 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carboxybenzofuran-5-yl)piperazine reaction with 2-chloro-l-methylpyridinium methanesulfonate gives 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine, m.p. 269-272° (hydrochloride).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05532241 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-3f263869f6464ca99454d09ebadc95d0 |
| Source note | uspto-grants-1996_07 |