Sodium Hydroxide → HCID 19438862, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 3.6 g of 1-[4-(5-methoxycarbonylindol-3-yl)butyl]-4-(chromen-4-on-6-yl)piperazine in 40 ml of THF is added dropwise with stirring at room temperature to a suspension of 0.6 g of lithium aluminum hyride in 20 ml of THF. The mixture is then stirred for a further hour at 25° C., 20 ml of dilute sodium hydroxide solution are added, the mixture is filtered and the filtrate is worked up in the customary manner. 1-[4-(5-Hydroxymethylindol-3-yl)butyl]-4-(chromen-4-on-6-yl)piperazine is obtained.

Provenance & Evidence