Hydrazine hydrate (1:1) → HCID 10759216, compound

HRID 1733981Notes

Reaction equation

C[N:2]([CH:4]=[C:5]1[CH2:11][CH2:10][N:9]([C:12](=[O:22])[C:13]2[CH:18]=[CH:17][C:16]([N+:19]([O-:21])=[O:20])=[CH:15][CH:14]=2)[C:8]2[CH:23]=[CH:24][CH:25]=[N:26][C:7]=2[C:6]1=O)C.O.[NH2:29]N>>[N+:19]([C:16]1[CH:17]=[CH:18][C:13]([C:12]([N:9]2[CH2:10][CH2:11][C:5]3[CH:4]=[N:2][NH:29][C:6]=3[C:7]3[N:26]=[CH:25][CH:24]=[CH:23][C:8]2=3)=[O:22])=[CH:14][CH:15]=1)([O-:21])=[O:20]

Participants

Reactant 2

HCID 24654Hydrazine hydrate (1:1)

HCID 54100772HCID 54100772, compound

Product 1

HCID 10759216HCID 10759216, compound

Procedure

As described for Reference Example 223, 8-[(dimethylamino)methylene]-5,6,7,8-tetrahydro-5-(4-nitrobenzoyl)-9H-pyrido[3,2-b]azepin-9-one is reacted with hydrazine hydrate to give the product as a solid, m.p. 255°-256° C.

Sources & evidence

ORD record: ord-5c48ae9b312f4176ac3e09cdbdc8a82c
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05532235

Reaction notes

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