反应详情

A solution of 3-(2-methyl-1,3-dioxolan-2-yl)benzylamine (57.2 g) in 1N hydrochloric acid (500 ml) and methanol (500 ml) was stirred at room temperature for 2 hours. The solvent was removed under reduced pressure. The residue was dissolved in methanol. The resulting precipitate was removed by filtration. The solvent was removed under reduced pressure. Recrystallization from a mixture of ethanol and acetone afforded 3-acetylbenzylamine hydrochloride (31.2 g).

1. customThe solvent was removed under reduced pressure
2. dissolutionThe residue was dissolved in methanol
3. customThe resulting precipitate was removed by filtration
4. customThe solvent was removed under reduced pressure
5. customRecrystallization
6. additionfrom a mixture of ethanol and acetone