Methyl iodide → HCID 178504024, compound

Participants

Reaction Steps

A suspension of 4-(3-acetylaminomethylphenyl)-2-thioureidothiazole (5.75 g) and methyl iodide (3.73 g) in methanol (100 ml) was refluxed for 2.5 hours. The solvent was removed under reduced pressure. The residue was crystallized from a mixture of methanol and ethyl acetate to afford 4-(3-acetylaminomethylphenyl)-2-(2-methyl-1-isothioureido)thiazole hydriodide (6.3 g).

Provenance & Evidence