Aluminum isopropoxide → 6-Amidino-2-naphthyl 5-(3-carboxypropionylaminomethyl)furan-2-carboxylate aluminium hydroxide hydrochloride

Participants

Reaction Steps

In 1.84 l of 95% ethanol was dissolved 18.4 g of 6-amidino-2-naphthyl 5-(3-carboxypropionylaminomethyl)furan-2-carboxylate hydrochloride, and a solution of 8.42 g of aluminium isopropoxide in 670 ml of toluene was added dropwise thereto at room temperature. After completion of the addition, the reaction mixture was stirred for 3 hours and allowed to stand overnight. The crystals thus precipitated were collected by filtration to obtain 19.1 g of the intended product.

Provenance & Evidence