HCID 53857553, compound → HCID 19707195, compound

HRID 1734192Notes

Reaction equation

HRID 1734192 reaction equation
[O:1]=[C:2]([CH3:24])[C:3](=[CH:9][C:10]1[CH:15]=[C:14]([C:16]([F:19])([F:18])[F:17])[CH:13]=[C:12]([C:20]([F:23])([F:22])[F:21])[CH:11]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5]>[Pd].C(OCC)(=O)C>[O:1]=[C:2]([CH3:24])[CH:3]([CH2:9][C:10]1[CH:11]=[C:12]([C:20]([F:21])([F:22])[F:23])[CH:13]=[C:14]([C:16]([F:17])([F:18])[F:19])[CH:15]=1)[C:4]([O:6][CH2:7][CH3:8])=[O:5]

Participants

4

Reactant 1

HCID 53857553HCID 53857553, compound

Product 1

HCID 19707195HCID 19707195, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8857Ethyl AcetateSolvent

Procedure

This compound is prepared in a manner analogous to that of Step B of Example 2, using 44.6 grams (0.126 mole) of ethyl 3-oxo-2-[3,5-di(trifluoromethyl)phenylmethylidene]butanoate and 1.5 grams (catalyst) of 5% palladium on charcoal in 250 mL of ethyl acetate, yielding ethyl 3-oxo-2-[3,5-di(trifluoromethyl)phenylmethyl]butanoate.

Workup

  1. customThis compound is prepared in a manner analogous to that of Step B of Example 2

Sources & evidence

ORD record
ord-5595eedd4f8b4b7ea6d0eeabb270d3c3
Source dataset
uspto-grants-1996_07
Patent number
US05532370

Reaction notes

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