Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-benzyloxy-2-(N,N-dimethylamino)methyl-4-pyridone → 2-(N,N-dimethylamino)methyl-5-hydroxy-4-pyridone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-benzyloxy-2-(N,N-dimethylamino)methyl-4-pyridone | HCID 67748049 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 2-(N,N-dimethylamino)methyl-5-hydroxy-4-pyridone | HCID 67748063 | 147.4% |
반응 단계
5-Benzyloxy-2-(N,N-dimethylamino) methyl-4-pyridone 1.0 g) in methanol (15 ml) was subjected to catalytic reduction with 10% palladium on activated carbon (200 mg) at atmospheric pressure. After removal of catalyst, the solution was concentrated under reduced pressure to give 2-(N,N-dimethylamino) methyl -5-hydroxy-4-pyridone (0.96 g).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05532354 |
| 출처 데이터셋 | uspto-grants-1996_07 |
| ORD ID | ord-d88c939e0f62467fb8cd38e914dacaa1 |
| 출처 메모 | uspto-grants-1996_07 |