HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 1-Benzyl-7-benzyloxy-3-bromo-2-methylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-Benzyl-7-benzyloxy-2-methylpyrrolo[2,3-d]pyridazine | HCID 19437740 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Benzyl-7-benzyloxy-3-bromo-2-methylpyrrolo[2,3-d]pyridazine | HCID 19437764 | 85% |
Reaction Steps
42.3 g (0.128 mol) of 1-benzyl-7-benzyloxy-2-methylpyrrolo[2,3-d]pyridazine and 6.6 ml (0.128 mol) of bromine are reacted in a total of 200 ml of dichloromethane as described for Example 3a. Yield: 85%, m.p.: 122°-123° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05534515 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-f5c0238201ef4d11aa51d2f8109999e4 |
| Source note | uspto-grants-1996_07 |