HuagongsheHuagongshe Chemistry Print Report · For research reference only
Bromine → 1-Benzyl-3-bromo-7-chloro-2-methylpyrrolo[2,3-d]pyridazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 1-Benzyl-7-chloro-2-methylpyrrolo[2,3-d]pyridazine | HCID 19437748 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 1-Benzyl-3-bromo-7-chloro-2-methylpyrrolo[2,3-d]pyridazine | HCID 19437770 | 83% |
Reaction Steps
8.0 g (31 mmol) of 1-benzyl-7-chloro-2-methylpyrrolo[2,3-d]pyridazine and 1.59 ml (31 mmol) of bromine are reacted in a total of 150 ml of dichloromethane as described for Example 3a. Yield: 83%, m.p.: 138°-140° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05534515 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-b7f7d0f3dbc24c5483e763f743a7d838 |
| Source note | uspto-grants-1996_07 |