Hydrochloric Acid → 4-Benzyl-N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

HRID 173455Notes

Reaction equation

HRID 173455 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[c:9]2[c:10]([n:11][c:12]([NH:14][c:15]3[cH:16][c:17]([O:27][CH3:28])[c:18](-[n:21]4[cH:22][n:23][c:24]([CH3:26])[cH:25]4)[cH:19][cH:20]3)[n:13]1)[CH2:29][CH2:30][N:31]([C:33]([O:34][C:35]([CH3:36])([CH3:37])[CH3:38])=[O:39])[CH2:32]2.[CH3:41][OH:42].[ClH:40]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[c:8]1[c:9]2[c:10]([n:11][c:12]([NH:14][c:15]3[cH:16][c:17]([O:27][CH3:28])[c:18](-[n:21]4[cH:22][n:23][c:24]([CH3:26])[cH:25]4)[cH:19][cH:20]3)[n:13]1)[CH2:29][CH2:30][NH:31][CH2:32]2

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 59333725tert-Butyl 4-benzyl-2-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenylamino)-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxylate

Product 1

HCID 593336984-Benzyl-N-(3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-amine

Sources & evidence

ORD record
ord-7e84383907d94bedafe2a68930b258d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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