Hydrochloric Acid → HCID 86749630, compound

HRID 1734880Notes

Reaction equation

HRID 1734880 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][C@H:13]([O:21][C:22](=[O:27])[CH2:23][N:24]([CH3:26])[CH3:25])[CH2:14]C2CCCCC2)=[CH:7][C:6]=1[NH:28][C:29](=[O:45])[CH2:30][CH:31]1[C:44]2[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=2[O:38][C:37]2[C:32]1=[CH:33][CH:34]=[CH:35][CH:36]=2)([CH3:4])([CH3:3])[CH3:2].[ClH:46]>O1CCOCC1>[ClH:46].[C:1]([C:5]1[CH:10]=[CH:9][C:8]([CH2:11][CH2:12][C@@:13]([O:21][C:22](=[O:27])[CH2:23][N:24]([CH3:26])[CH3:25])([CH2:2][CH2:1][CH:5]2[CH2:10][CH2:9][CH2:8][CH2:7][CH2:6]2)[CH3:14])=[CH:7][C:6]=1[NH:28][C:29](=[O:45])[CH2:30][CH:31]1[C:44]2[CH:43]=[CH:42][CH:41]=[CH:40][C:39]=2[O:38][C:37]2[C:32]1=[CH:33][CH:34]=[CH:35][CH:36]=2)([CH3:4])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 53852169HCID 53852169, compound

Product 1

HCID 86749630HCID 86749630, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Following a procedure similar to that described in Example 119, but using N,N-dimethylglycine (S)-1-(2-{4-t-butyl-3-[2-(9H-xanthen-9-yl)acetamido]phenyl}ethyl)-2-cyclohexylethyl ester (prepared as described in Example 120) and a 4N solution of hydrogen chloride in dioxane as starting materials, in relative proportions similar to those used in that Example, the title compound was obtained as a foam-like material.

Sources & evidence

ORD record
ord-b7950fb55b8f40348ecdf4d73b23f10c
Source dataset
uspto-grants-1996_07
Patent number
US05534529

Reaction notes

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