HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19068935, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl Thioglycolate | HCID 16907 | — |
| Reactant | 3-Acetyl-2-chloro-1-methylindole | HCID 820344 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 19068935 | HCID 19068935 | — |
Reaction Steps
450 μl of methyl 2-mercaptoacetate was added to a slurry of 870 mg of (76) and 1.2 g of K2CO3 in 10 ml of MeOH. The reaction was stirred overnight. 30 ml of water was added, stirring continued for 1 hour, and the product filtered off giving 160 mg of product. Recrystallization from MeOH gave 30 mg of (77). M.p. 165.5°-166.8° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536721 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-31a2b7d979fc4a83babe98c9a368a9d4 |
| Source note | uspto-grants-1996_07 |