HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → HCID 19068979, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1-(2-Chloro-1H-indol-3-yl)ethan-1-one | HCID 10932307 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19068979 | HCID 19068979 | — |
Reaction Steps
To a slurry of 400 mg of NaH in 20 ml THF was added 1 g of (75), and then 770 μl of benzyl bromide. The reaction was left with stirring for 3 days. Water was added, and the product extracted with diethylether, dried, and the solvent evaporated off to give 1.52 g of a redbrown powder, which was used without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536721 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-0ca8ca27525c4a3a86175dff9f4f6143 |
| Source note | uspto-grants-1996_07 |