Cyanuric chloride → HCID 19436864, compound

Participants

Reaction Steps

Cyanuric chloride (2.0 g, 10.85 mM) was dispersed in dioxane (80 mL) with stirring and 2-(3,4-dimethoxyphenyl)ethylamine (3.93 g, 21.68 mM) was introduced dropwise over 2 minutes. Sodium hydroxide (1N, 24 mL) was added dropwise over 5 minutes then the whole was brought to reflux for 18 hours. Cooling to ambient temperature caused a white solid to precipitate. Diethyl ether (100 mL) was introduced to fully precipitate the product which was filtered, rinsed with diethyl ether and dried. 5.05 g, (98%), mp=186°-186.5° C.

Provenance & Evidence