HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-[(2-phenylbenzoyl)amino]benzoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methyl 4-[(biphenyl-2-carbonyl)-amino]-benzoate | HCID 7901139 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-[(2-phenylbenzoyl)amino]benzoic Acid | HCID 10543502 | — |
Reaction Steps
A 3.15 g sample of methyl 4-[([1,1'-biphenyl]-2-carbonyl)amino]benzoate is refluxed for 8 hours in 100 ml of ethyl alcohol and 2.5 ml of 10N sodium hydroxide. The cooled reaction mixture is acidified with hydrochloric acid and the desired product collected and dried to give 2.9 g of the desired product as a solid m.p. 246°-249° C. M+H=318 .
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05536718 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-93ee16081dce48c1b33d701aa0c2bd14 |
| Source note | uspto-grants-1996_07 |