Hydrochloric Acid → HCID 18917485, compound

Participants

Reaction Steps

To a solution of 1.0 g of N-[5-(5H-pyrrolo-[2, 1-c][1,4]benzodiazepin-10(11H) -ylcarbonyl) -2-pyridinyl]-2-methylpyridine-3-carboxamide in 50 ml of methanol is added hydrogen chloride gas. The mixture is stirred at room temperature for 30 minutes and the solvent removed under vacuum. The residue is triturated with ether to give 1.0 g of the desired product as a solid: mass spectrum(CCl) ;459 (M+).

Provenance & Evidence