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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1735305Generated: October 31, 2026

4-(2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)cyclohexanone → 2,4-Diamino-6-(2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl)-5,6,7,8-tetrahydroquinazoline

https://huagongshe.com/reaction/1735305

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2,3-Dihydro-2,2-dimethylbenzofuran-7-ylmethyl)cyclohexanoneHCID 19705260—
ReactantHCID 178418324HCID 178418324—
SolventDiethylene Glycol Monoethyl EtherHCID 8146—
Product2,4-Diamino-6-(2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl)-5,6,7,8-tetrahydroquinazolineHCID 19705212—

Reaction Steps

This compound is prepared in a manner analogous to that of Example 1, using 3.4 grams (0.013 mole) of 4-(2,3-dihydro-2,2-dimethylbenzofuran- 7-ylmethyl)cyclohexanone and 1.2 grams (0.014 mole) of cyanoguanidine in 2-(2-ethoxyethoxy)ethanol, yielding 2,4-diamino-6-(2,3-dihydro-2,2-dimethylbenzofuran-7-ylmethyl)-5,6,7,8-tetrahydroquinazoline.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05536725
Source datasetuspto-grants-1996_07
ORD IDord-f89a92292b8e4d51b77ccd043b70c173
Source noteuspto-grants-1996_07