Oxalyl chloride → HCID 53948551, compound

HRID 1735692Notes

Reaction equation

HRID 1735692 reaction equation
[C:1]([CH2:4][C@@H:5]([CH2:16][CH:17]([CH3:19])[CH3:18])[C:6]([O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:7])(O)=[O:2].C(Cl)(=O)C([Cl:23])=O>ClCCl>[Cl:23][C:1]([CH2:4][C@@H:5]([CH2:16][CH:17]([CH3:19])[CH3:18])[C:6]([O:8][CH2:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1)=[O:7])=[O:2]

Participants

4

Reactant 2

HCID 65578Oxalyl chlorideHCID 22874407HCID 22874407, compound

Product 1

HCID 53948551HCID 53948551, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of benzyl (2R)-2-(carboxymethyl)-4-methylvalerate (500 mg) in dry dichloromethane (10 ml) was added oxalyl chloride (0.2 ml) at 0° C. After the solution was stirred at the same temperature for 1 hour, the solvent was evaporated in vacuo to give benzyl (2R)-2-(chloro-carbonylmethyl)-4-methylvalerate (522 mg) as an oil.

Workup

  1. customthe solvent was evaporated in vacuo

Sources & evidence

ORD record
ord-ad30c1c0639a4a15983b2c9aef345d9a
Source dataset
uspto-grants-1996_07
Patent number
US05538950

Reaction notes

Loading…