HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperazine, 1-(3-chloropropyl)-4-phenyl- → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperazine, 1-(3-chloropropyl)-4-phenyl- | HCID 139197 | — |
| Reactant | HCID 13803747 | HCID 13803747 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | methyl 3-oxo-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydro-2H-1,5-benzoxathiepine-4-carboxylate | HCID 19434348 | — |
Reaction Steps
Methyl 3-oxo-3,4-dihydro-2H-1,5-benzoxathiepine-4-carboxylate was condensed with 3-(4-phenylpiperazin-1-yl)propyl chloride in the same manner as in Reference Example 1 to isolate methyl 3-oxo-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydro-2H-1,5-benzoxathiepine-4-carboxylate as hydrochloride. Recrystallization from methanol yielded white crystals, melting point 176°-178° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05538974 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-4d3e51ffb1b748e680579ffceecfc33c |
| Source note | uspto-grants-1996_07 |