Sodium Acetate → HCID 178475157, compound

Participants

Reaction Steps

To a solution of 0.13 g of aminoguanidine hydrogencarbonate, 2.00 g of sodium acetate in 25 ml of 0.2M acetic acid a solution of 0.30 g 3-oxo-14β-hydroxy-5β-androstane-17β-carboxaldehyde (Prepn. 5) in 40 ml of dioxane was added dropwise. After 2 hrs the mixture was evaporated to dryness under reduced pressure and the crude product was extracted three times with iso-propanol. Evaporation of the solvent gave 0.30 g of (E)-3-oxo-17β-guanidinoiminomethyl-5β-androstane-14β-ol acetate as a white foam.

Provenance & Evidence