Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triphosgene | HCID 94429 | — |
| Reactant | 1-Amino thymine | HCID 11819159 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 19076265 | HCID 19076265 | — |
Reaction Steps
1-Amino thymine (7, 12.5 g, 0.1 mol) is dissolved in tetrahydrofuran (500 mL) and the solution is cooled to 0° C. and a 2M solution of triphosgene in THF (150 mL) is added and the reaction is stirred for 4 hours. The solution is evaporated to a solid, which is used as is in the next reaction.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US05539082 |
|---|
| Source dataset | uspto-grants-1996_07 |
|---|
| ORD ID | ord-83ba5ceef3a84098b64a3d73fb7698e3 |
|---|
| Source note | uspto-grants-1996_07 |
|---|
