HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 15346993, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 15346992 | HCID 15346992 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 15346993 | HCID 15346993 | 79.3% |
Reaction Steps
0.83 g of Compound 22 was dissolved in 12 ml of dioxane, 8 ml of concentrated hydrochloric acid was added and the mixture was heated at reflux for 4 hours. The reaction solution was cooled on ice and adjusted to pH 8 by addition of a 10N aqueous solution of sodium hydroxide thereto, and the precipitated crystals were collected by filtration to give 605 mg (79%) of Compound 23.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05539112 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-61c25e91cecb460698feeb2495369fc3 |
| Source note | uspto-grants-1996_07 |