HCID 19434937, compound → HCID 19434837, compound

Participants

Reaction Steps

Substantially the same manner as that in Example 127 (4) was repeated except that 600 mg (1.21 mmol) of the above 6,8-difluoro-2-(3-fluoro-4-pivaloylaminophenyl)-5-[3-(imidazol-1-yl)propylamino]-4H-1-benzopyran-4-one was used, treatment with 20 mL of concentrated sulfuric acid was carried out and the resulting compound was recrystallized from methanol, to give 341 mg of Compound 129 (yield: 68%).

Provenance & Evidence