HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → N-(4,7-dimethyl-5-benzimidazolyl)-N'-2-aminoethylthiourea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Ethylenediamine | HCID 3301 | — |
| Reactant | 4,7-Dimethyl-5-benzimidazolylisothiocyanate | HCID 21472724 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-(4,7-dimethyl-5-benzimidazolyl)-N'-2-aminoethylthiourea | HCID 21472717 | — |
Reaction Steps
A solution of 4,7-dimethyl-5-benzimidazolylisothiocyanate (0.59 g) in CH2Cl2 (50 mL)/methanol (5 mL) is added dropwise over 20 minutes to ethylenediamine (1 mL) in solution in CH2Cl2 (150 mL). The mixture is stirred for 2 hours at room temperature. The resulting suspension is filtered and the solid is dried overnight in vacuo to afford N-(4,7-dimethyl-5-benzimidazolyl)-N'-2-aminoethylthiourea as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05541210 |
| Source dataset | uspto-grants-1996_07 |
| ORD ID | ord-3c8348cbcc1f4a1f813f5bc8b5cd5245 |
| Source note | uspto-grants-1996_07 |