Water → HCID 4184921, compound

HRID 1736734Notes

Reaction equation

HRID 1736734 reaction equation
[N+:1]([C:4]1[CH:10]=[C:9]([O:11][CH3:12])[CH:8]=[CH:7][C:5]=1[NH2:6])([O-:3])=[O:2].[C:13](Cl)(=[O:18])[CH2:14][CH2:15][CH2:16][CH3:17].O>N1C=CC=CC=1>[C:13]([NH:6][C:5]1[CH:7]=[CH:8][C:9]([O:11][CH3:12])=[CH:10][C:4]=1[N+:1]([O-:3])=[O:2])(=[O:18])[CH2:14][CH2:15][CH2:16][CH3:17]

Participants

5

Reactant 3

HCID 962WaterHCID 61186Valeryl chlorideHCID 667934-Methoxy-2-nitroaniline

Product 1

HCID 4184921HCID 4184921, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Conditions

Temperature
0 °C

Procedure

4.2 g (0.025 mol) of 2-nitro-4-methoxy-aniline are dissolved in 30 ml of pyridine, cooled to 0° C. and treated with 3.3 g (0.0275 mol) of valeryl chloride with stirring. After stirring for 1 hour at ambient temperature, the mixture is poured into iced water, the crystals are filtered off under suction and dried.

Workup

  1. stirringAfter stirring for 1 hour at ambient temperature
  2. filtrationthe crystals are filtered off under suction
  3. customdried

Sources & evidence

ORD record
ord-1c890ec182e64bada1bcec7e25b7e916
Source dataset
uspto-grants-1996_07
Patent number
US05541229

Reaction notes

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