Trifluoroacetic acid → HCID 15069282, compound

HRID 1736755Notes

Reaction equation

[CH:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:15]=[CH:14][C:13]([C:16]3[C:17]([C:22]([O:24]C(C)(C)C)=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:12][CH:11]=2)[C:7]2[CH:29]=[CH:30][CH:31]=[CH:32][C:6]=2[N:5]=1)([CH3:3])[CH3:2].FC(F)(F)C(O)=O>>[CH:1]([C:4]1[N:8]([CH2:9][C:10]2[CH:11]=[CH:12][C:13]([C:16]3[C:17]([C:22]([OH:24])=[O:23])=[CH:18][CH:19]=[CH:20][CH:21]=3)=[CH:14][CH:15]=2)[C:7]2[CH:29]=[CH:30][CH:31]=[CH:32][C:6]=2[N:5]=1)([CH3:3])[CH3:2]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 15069141HCID 15069141, compound

Product 1

HCID 15069282HCID 15069282, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-isopropyl-benzimidazol-1-yl)-methyl]-biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-0b7d3d38ab4b4f3199faaad223d7bce4
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541229

Reaction notes

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