Trifluoroacetic acid → HCID 67733246, compound

HRID 1736756Notes

Reaction equation

[CH2:1]([O:8][C:9]1[C:14]2[N:15]([CH2:22][C:23]3[CH:28]=[CH:27][C:26]([C:29]4[C:30]([C:35]([O:37]C(C)(C)C)=[O:36])=[CH:31][CH:32]=[CH:33][CH:34]=4)=[CH:25][CH:24]=3)[C:16]([CH2:18][CH2:19][CH2:20][CH3:21])=[N:17][C:13]=2[C:12]([CH3:42])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[F:43][C:44]([F:49])([F:48])[C:45]([OH:47])=[O:46]>>[F:43][C:44]([F:49])([F:48])[C:45]([OH:47])=[O:46].[CH2:1]([O:8][C:9]1[C:14]2[N:15]([CH2:22][C:23]3[CH:24]=[CH:25][C:26]([C:29]4[C:30]([C:35]([OH:37])=[O:36])=[CH:31][CH:32]=[CH:33][CH:34]=4)=[CH:27][CH:28]=3)[C:16]([CH2:18][CH2:19][CH2:20][CH3:21])=[N:17][C:13]=2[C:12]([CH3:42])=[CH:11][CH:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 15069205HCID 15069205, compound

Product 1

HCID 67733246HCID 67733246, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(7-benzyloxy-2-n-butyl-4-methyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-9c602499081543299240e4e501eb3737
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541229

Reaction notes

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