HCID 15069205, compound → HCID 15069242, compound

HRID 1736780Notes

Reaction equation

HRID 1736780 reaction equation
[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18]([C:23]([O:25][C:26]([CH3:29])([CH3:28])[CH3:27])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[C:30]([O:35]CC3C=CC=CC=3)=[CH:31][CH:32]=[C:33]([CH3:34])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].[H][H]>CO.[OH-].[OH-].[Pd+2]>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:12]=[CH:13][C:14]([C:17]3[C:18]([C:23]([O:25][C:26]([CH3:29])([CH3:27])[CH3:28])=[O:24])=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:15][CH:16]=2)[C:8]2[C:30]([OH:35])=[CH:31][CH:32]=[C:33]([CH3:34])[C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 2

HCID 15069205HCID 15069205, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 15069242HCID 15069242, compound

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 887MethanolSolvent

Procedure

Prepared in analogous manner to Example 57 from tert.butyl 4'-[(2-n-butyl-4-methyl-7-benzyloxy-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and hydrogen in the presence of palladium hydroxide on carbon in methanol.

Sources & evidence

ORD record
ord-3d60fabeae734d55a0aacab81a8d34e1
Source dataset
uspto-grants-1996_07
Patent number
US05541229

Reaction notes

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