Trifluoroacetic acid → HCID 10366029, compound

HRID 1736835Notes

Reaction equation

[NH:1]([C:5]1[CH:6]=[CH:7][C:8]2[N:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH3:16])[N:10]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]4[C:25]([C:30]([O:32]C(C)(C)C)=[O:31])=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:20][CH:19]=3)[C:9]=2[CH:37]=1)[C:2]([CH3:4])=[O:3].FC(F)(F)C(O)=O>>[NH:1]([C:5]1[CH:6]=[CH:7][C:8]2[N:12]=[C:11]([CH2:13][CH2:14][CH2:15][CH3:16])[N:10]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]4[C:25]([C:30]([OH:32])=[O:31])=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:20][CH:19]=3)[C:9]=2[CH:37]=1)[C:2]([CH3:4])=[O:3]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 10368615HCID 10368615, compound

Product 1

HCID 10366029HCID 10366029, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(6-acetamino-2-n-butyl-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-4c6f85b4b7734beaa47cf61055a72f6d
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541229

Reaction notes

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