Trifluoroacetic acid → HCID 86749692, compound

HRID 1736860Notes

Reaction equation

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[CH:15][C:14]([C:17]3[C:18](C(OC(C)(C)C)=O)=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([N:34]3[C:41](=[O:42])[CH:40]4[N:36]([CH2:37][S:38][CH2:39]4)[C:35]3=[O:43])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].FC(F)(F)[C:46]([OH:48])=[O:47]>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[C:15]([C:46]([OH:48])=[O:47])[C:14]([C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([N:34]3[C:41](=[O:42])[CH:40]4[N:36]([CH2:37][S:38][CH2:39]4)[C:35]3=[O:43])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 67572741HCID 67572741, compound

Product 1

HCID 86749692HCID 86749692, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-6-(5,7-dioxo-1H,3H-imidazo-[1,5-c]thiazol-6-yl)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-b31578330245420ba3b937dc44570b6e
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541229

Reaction notes

Loading…