Trifluoroacetic acid → HCID 57040927, compound

HRID 1736870Notes

Reaction equation

[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=C[C:14]([C:17]3[C:18](C(OC(C)(C)C)=O)=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([N:34]([CH3:40])[C:35]([O:37][CH2:38][CH3:39])=[O:36])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4].F[C:42](F)(F)[C:43]([OH:45])=[O:44]>>[CH2:1]([C:5]1[N:9]([CH2:10][C:11]2[CH:16]=[C:42]([C:43]([OH:45])=[O:44])[C:14]([C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)=[CH:13][CH:12]=2)[C:8]2[CH:30]=[C:31]([N:34]([CH3:40])[C:35]([O:37][CH2:38][CH3:39])=[O:36])[CH:32]=[CH:33][C:7]=2[N:6]=1)[CH2:2][CH2:3][CH3:4]

Participants

Reactant 2

HCID 6422Trifluoroacetic acid

HCID 86749695HCID 86749695, compound

Product 1

HCID 57040927HCID 57040927, compound

Procedure

Prepared in analogous manner to Example 9 from tert.butyl 4'-[(2-n-butyl-6-(N-ethoxycarbonyl-methylamino)-benzimidazol-1-yl)-methyl]biphenyl-2-carboxylate and trifluoroacetic acid.

Sources & evidence

ORD record: ord-155ec2a6aa124349b7040e9e5ef99cc7
Source dataset: uspto-grants-1996_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05541229

Reaction notes

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