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HRID1737047

反应详情

EQUATION

反应方程式

HRID 1737047 的结构方程式

REACTANTS

反应物

2
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：O=C(c1cc(Cl)cc(Cl)c1)N1CC[C@H](N(CCc2ccccc2)C(=O)C(F)(F)F)C[C@H]1Cc1ccccc1
HCID57094766

未命名化合物

PRODUCTS

生成物

1
结构：O=C(c1cc(Cl)cc(Cl)c1)N1CC[C@H](NCCc2ccccc2)C[C@H]1Cc1ccccc1
HCID57150363

未命名化合物

PROCEDURE

实验过程

0.130 g (0.231 mmol) of (2R*,4S*)-2-benzyl-1-(3,5-dichlorobenzoyl)-N-(2-phenylethyl)-N-trifluoroacetyl-4-piperidinamine is reacted with 0.035 g (0.923 mmol) of sodium borohydride in analogy to Example 2. The title compound ##STR81## is obtained (0.101 g, 94%) as oil. TLC: methylene chloride/methanol/conc. ammonia (700:50:1) Rf =0.34, FD-MS: M+ =466, 468.