Serinol → HCID 15428265, compound

Participants

Reaction Steps

A stirred solution of 1.84 g (20.0 mmol) of serinol in 4.25 mL (20.1 mmol) of hexamethyldisilazane containing 1 drop of bromotrimethylsilane was heated to 180° C. under argon. After 16 h, the reaction mixture was partially cooled and distilled at 0.6 Torr, collecting the fraction with bp 44-47° C. to give title compound as a colorless liquid, 4.05 g, 86%.

Provenance & Evidence