1,1-Dimethylhydrazine → HCID 21841973, compound

HRID 1737216Notes

Reaction equation

HRID 1737216 reaction equation
[CH3:1][O:2][C:3]([C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=1[N:11]=[C:12]=[O:13])=[O:4].[CH3:14][N:15]([CH3:17])[NH2:16]>C1(C)C=CC=CC=1>[CH3:14][N:15]([CH3:17])[NH:16][C:12]([NH:11][C:6]1[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=1[C:3]([O:2][CH3:1])=[O:4])=[O:13]

Participants

4

Reactant 2

HCID 59761,1-DimethylhydrazineHCID 519494Methyl 2-isocyanatobenzoate

Product 1

HCID 21841973HCID 21841973, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of 300 mL of toluene containing 50 g of 2-methoxycarbonylphenyl isocyanate at 0° C. under a nitrogen atmosphere was added dropwise 21.44 mL of 1,1-dimethylhydrazine. The reaction mixture was allowed to warm to room temperature and stirred overnight. The mixture was then cooled to approximately 0° C., filtered, and the solid was rinsed with hexane to give 61.5 g of the title compound of Step A as a white solid.

Workup

  1. temperatureThe mixture was then cooled to approximately 0° C.
  2. filtrationfiltered
  3. washthe solid was rinsed with hexane

Sources & evidence

ORD record
ord-5b7c41ecb99b48439ca52bd2c914cbd5
Source dataset
uspto-grants-1999_10
Patent number
US05962436

Reaction notes

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